Role of Systemic Enzymes in Infections

Enzymes are complex macromolecules of amino-acids which bio-catalyse various body processes. Adequate concentrations of enzymes are essential for optimal functioning of the immune system. During infections, body’s enzymatic system is attacked and hence the immune system is also likely to derange. This may be detrimental for the host’s well-being and existence. Along with appropriate antimicrobial therapy, administration of enzymes externally could plausibly help to stabilise this disturbed immune system and thus assist the body to overcome the infections. This would especially be useful in multi-drug resistant and severe nosocomial infections. Enzymes have been studied and found to play a supplementary role in control of these infections. They also seem to help in control of difficult to manage viral infections. Besides, their use has been found to be beneficial in prevention of various common infections such as flu and cold. In spite of their potential, they have remained largely underestimated and underexploited. This review on oral enzymes attempts to highlight the role and safety of enzymes as adjunctive therapy in infections.